AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |
Back to Blog
Lumen anatomy1/31/2024 ![]() Intercalated cells (peg cells, Secretory cells (~60%), nonciliated, contain apical granules and produce tubular fluid, progesterone increases their number while estrogen increases their height and secretory activity.Ciliated columnar cells (~25%), most abundant in infundibulum and ampulla, estrogen increases production of cilia.Mucosa: consists predominately of single layer of cells including:.Plica: delicate folds of mucosa on inner aspect of tube, most evident in ampulla, merge with fimbriae.Uterotubal junction: entrance to uterine cavity.Tubal ostium: opening to peritoneal cavity.Segments: intramural (within wall of uterus), isthmus (thick walled, narrower opening, ~ 2 cm in length), ampulla (thin walled, major portion of lateral tube, typically where fertilization occurs), infundibulum (trumpet shaped end lined by fimbriae, attaches to ovary).Lymphatic drainage to para aortic, internal iliac, external iliac, common iliac and inguinal nodes.Sensory fibers run from T11 - T12 and L1.Nerve supply from both sympathetic and parasympathetic fibers.Arterial supply from branches of uterine and ovarian arteries, located within mesosalpinx.Connected to broad ligament by mesosalpinx (double fold of peritoneum), to uterine cornu by utero ovarian ligament, to lateral pelvic sidewall by infundibulopelvic (suspensory) ligament.Extends from posterior superior uterine fundus laterally and leads to ovaries.Hollow, tubular structures, bilateral, 8 - 12 cm long and 0.5 - 1.2 cm in diameter, lined by a single layer of mucosal epithelium with many folds (plica).Reference: Bhatnagar: Essentials of Human Embryology, Third Edition, 2000.The Müllerian remant is the rudimentary appendix testis.Testes produce Müllerian inhibitory substance, which causes regression of Müllerian ducts and persistence of paired Wolffian (mesonephric) ducts, which form epididymis and vas deferens.Development affected by clomiphene, tamoxifen and to a lesser extent diethylstilbestrol (DES) ( Hum Pathol 1987 18:1132, Hum Pathol 1982 13:190).Müllerian structures persist and Wolffian (mesonephric) duct regresses vestiges may persist as epithelial inclusions.In a female fetus (or male without functioning testis):.Fused part forms uterus and upper vagina.Unfused cephalic part of Müllerian ducts form fallopian tube.This site of invagination later becomes the tubal ostium in which the fimbriae develop septation of the cloaca occurs.Müllerian (paramesonephric) ducts form from coelomic epithelium invaginating venterolaterally into Wolffian (mesonephric) duct and genital mesentery.Migration of primordial germ cells from yolk sac, genital ridge forms from intermediate mesoderm, cloaca forms.
0 Comments
Read More
Leave a Reply. |